The Soh Laboratory Group at University of California, Santa Barbara works to develop novel materials and devices to improve the condition of human health. Our laboratory consists of researchers from many disciplines, including Physics, Chemistry, and diverse areas of engineering such as Materials, Mechanical, Chemical, and Electrical Engineering. Currently, our research focuses on two main themes: Directed Evolution of Materials and Integrated Biosensors. These two technologies hold the promise for early detection and personalized treatment for many diseases including Alzheimer’s, cancer, and diabetes.
- Our MEDIC technology is showcased on Healthline.com. [click for link]
- Chemical and Engineering News highlights our MEDIC technology, calling it "clever with a capital C." [click for link]
- Science Magazine highlights Dr. Scott Ferguson's article which made the cover of Science Translational Medicine. [click for link]
- Read about Royal Society of Chemistry's highlight of our MEDIC platform. [click for link]
- Our work in aptamer generation is highlighted in Nature Methods. [click for link]
- Dr. Seung Soo Oh is awarded the prestigious Baxter Young Investigator Award for Postdoctoral Fellows. [click for link]
- Mr. Peter Mage wins the UCSB Grad Slam Challenge. [click for video] or [more info]
- Dr. Allen Yang's work on cell sorting is highlighted by Chemical & Engineering News. [click for link]
- Ms. Faye Fong is awarded the prestigious California Institute of Regenerative Medicine (CIRM) fellowship for pre-doctoral students. [click for link]
- Archived News
- A. H. J. Yang et al., "Accurate Zygote-Specific SNP Discrimination Using Microfluidic Electrochemical DNA Melt Curves," Angew. Chemie. Int'l Ed. (accepted 2013)
B. S. Ferguson et al., "Real-time, aptamer-based tracking of circulating therapeutic agents in living animals," Science Translational Medicine, 5, 213ra165 (2013).
S. S. Oh et. al., "In Vitro Selection of Shape-Changing DNA Nanostructures Capable of Binding-Induced Cargo Release," ACS Nano, 7 (11) 9675–9683 (2013).
M. Cho et al. "Quantitative Selection and Parallel Characterization of Aptamers" Proceedings of the National Academy of Sciences, 110 (46), USA (2013).
K. Hsieh et. al., "Rapid, Sensitive, and Quantitative Detection of Pathogenic DNA at the Point of Care via Microfluidic Electrochemical Quantitative Loop-Mediated Isothermal Amplification" Angewandte Chemie International Edition Vol. 51, 4896-4900 (2012).
Q. Gong et. al., "Selection Strategy to Generate Aptamer Pairs that Bind to Distinct Sites on Protein Target," Analytical Chemistry Vol. 84, 5365−5371 (2012).